Functional Gene Knockout of NRF2 Increases Chemosensitivity of Human Lung Cancer A549 Cells In Vitro and in a Xenograft Mouse Model

Recent studies point to the evolution of drug resistance in lung cancer as being centered, at least in part, on the upregulation of various genes involved in controlling efflux or drug inactivation. Among the most important of these genes is Nuclear Factor Erythroid 2-Related Factor (NRF2), consider...

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Detalles Bibliográficos
Autores principales: Bialk, Pawel, Wang, Yichen, Banas, Kelly, Kmiec, Eric B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251792/
https://www.ncbi.nlm.nih.gov/pubmed/30505938
http://dx.doi.org/10.1016/j.omto.2018.10.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251792/
https://www.ncbi.nlm.nih.gov/pubmed/30505938
http://dx.doi.org/10.1016/j.omto.2018.10.002

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