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Poly-Target Selection Identifies Broad-Spectrum RNA Aptamers

Aptamer selections often yield distinct subpopulations, each with unique phenotypes that can be leveraged for specialized applications. Although most selections aim to attain ever higher specificity, we sought to identify aptamers that recognize increasingly divergent primate lentiviral reverse tran...

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Detalles Bibliográficos
Autores principales: Alam, Khalid K., Chang, Jonathan L., Lange, Margaret J., Nguyen, Phuong D.M., Sawyer, Andrew W., Burke, Donald H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251793/
https://www.ncbi.nlm.nih.gov/pubmed/30472639
http://dx.doi.org/10.1016/j.omtn.2018.10.010