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Arrestins: structural disorder creates rich functionality

Arrestins are soluble relatively small 44–46 kDa proteins that specifically bind hundreds of active phosphorylated GPCRs and dozens of non-receptor partners. There are binding partners that demonstrate preference for each of the known arrestin conformations: free, receptor-bound, and microtubule-bou...

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Detalles Bibliográficos
Autores principales: Gurevich, Vsevolod V., Gurevich, Eugenia V., Uversky, Vladimir N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251804/
https://www.ncbi.nlm.nih.gov/pubmed/29453740
http://dx.doi.org/10.1007/s13238-017-0501-8