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The enzymatic biosynthesis of acylated steroidal glycosides and their cytotoxic activity

Herein we describe the discovery and functional characterization of a steroidal glycosyltransferase (SGT) from Ornithogalum saundersiae and a steroidal glycoside acyltransferase (SGA) from Escherichia coli and their application in the biosynthesis of acylated steroidal glycosides (ASGs). Initially,...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Kong, Jian-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251810/
https://www.ncbi.nlm.nih.gov/pubmed/30505666
http://dx.doi.org/10.1016/j.apsb.2018.04.006