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Recent developments in topoisomerase-targeted cancer chemotherapy
The DNA topoisomerase enzymes are essential to cell function and are found ubiquitously in all domains of life. The various topoisomerase enzymes perform a wide range of functions related to the maintenance of DNA topology during DNA replication, and transcription are the targets of a wide range of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251812/ https://www.ncbi.nlm.nih.gov/pubmed/30505655 http://dx.doi.org/10.1016/j.apsb.2018.07.008 |