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Recent developments in topoisomerase-targeted cancer chemotherapy

The DNA topoisomerase enzymes are essential to cell function and are found ubiquitously in all domains of life. The various topoisomerase enzymes perform a wide range of functions related to the maintenance of DNA topology during DNA replication, and transcription are the targets of a wide range of...

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Detalles Bibliográficos
Autores principales: Hevener, KirkE., Verstak, Tatsiana A., Lutat, Katie E., Riggsbee, Daniel L., Mooney, Jeremiah W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251812/
https://www.ncbi.nlm.nih.gov/pubmed/30505655
http://dx.doi.org/10.1016/j.apsb.2018.07.008