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Local Effects Following Single and Repeat Intra-Articular Injections of Triamcinolone Acetonide Extended-Release: Results from Three Nonclinical Toxicity Studies in Dogs

INTRODUCTION: Single intra-articular (IA) injections of poly(lactic-co-glycolic acid) (PLGA) microsphere-based triamcinolone acetonide extended-release (TA–ER; formerly FX006) demonstrated sustained, clinically relevant benefits in patients with knee osteoarthritis. The local effects of TA–ER were a...

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Detalles Bibliográficos
Autores principales: Bodick, Neil, Williamson, Toni, Strand, Vibeke, Senter, Becca, Kelley, Scott, Boyce, Rogely, Lightfoot-Dunn, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Healthcare 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251841/
https://www.ncbi.nlm.nih.gov/pubmed/30203389
http://dx.doi.org/10.1007/s40744-018-0125-3