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AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair
Double-strand breaks (DSBs) are the most lethal DNA damages induced by ionising radiation (IR) and their efficient repair is crucial to limit genomic instability. The cellular DSB response after low IR doses is of particular interest but its examination requires the analysis of high cell numbers. He...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251879/ https://www.ncbi.nlm.nih.gov/pubmed/30470760 http://dx.doi.org/10.1038/s41598-018-35660-5 |