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AutoFoci, an automated high-throughput foci detection approach for analyzing low-dose DNA double-strand break repair

Double-strand breaks (DSBs) are the most lethal DNA damages induced by ionising radiation (IR) and their efficient repair is crucial to limit genomic instability. The cellular DSB response after low IR doses is of particular interest but its examination requires the analysis of high cell numbers. He...

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Detalles Bibliográficos
Autores principales: Lengert, Nicor, Mirsch, Johanna, Weimer, Ratna N., Schumann, Eik, Haub, Peter, Drossel, Barbara, Löbrich, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251879/
https://www.ncbi.nlm.nih.gov/pubmed/30470760
http://dx.doi.org/10.1038/s41598-018-35660-5