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New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis

Circulating cell-free DNA (cfDNA) has received increasing interest as an apparent breakthrough approach in diagnostics, personalized medicine, and tumor biology. However, the structural features of cfDNA are poorly characterized. Specifically, the literature has discrepancies with regards to cfDNA s...

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Detalles Bibliográficos
Autores principales: Sanchez, Cynthia, Snyder, Matthew W., Tanos, Rita, Shendure, Jay, Thierry, Alain R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251887/
https://www.ncbi.nlm.nih.gov/pubmed/30479833
http://dx.doi.org/10.1038/s41525-018-0069-0