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New insights into structural features and optimal detection of circulating tumor DNA determined by single-strand DNA analysis
Circulating cell-free DNA (cfDNA) has received increasing interest as an apparent breakthrough approach in diagnostics, personalized medicine, and tumor biology. However, the structural features of cfDNA are poorly characterized. Specifically, the literature has discrepancies with regards to cfDNA s...
Autores principales: | Sanchez, Cynthia, Snyder, Matthew W., Tanos, Rita, Shendure, Jay, Thierry, Alain R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251887/ https://www.ncbi.nlm.nih.gov/pubmed/30479833 http://dx.doi.org/10.1038/s41525-018-0069-0 |
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