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Mediated nuclear import and export of TAZ and the underlying molecular requirements

Nucleocytoplasmic distribution of Yap/TAZ is regulated by the Hippo pathway and the cytoskeleton. While interactions with cytosolic and nuclear “retention factors” (14–3–3 and TEAD) are known to control their localization, fundamental aspects of Yap/TAZ shuttling remain undefined. It is unclear if t...

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Detalles Bibliográficos
Autores principales: Kofler, Michael, Speight, Pam, Little, Darby, Di Ciano-Oliveira, Caterina, Szászi, Katalin, Kapus, András
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251892/
https://www.ncbi.nlm.nih.gov/pubmed/30470756
http://dx.doi.org/10.1038/s41467-018-07450-0