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Cyclic undecapeptide Cyclosporin A mediated inhibition of amyloid synthesis: Implications in alleviation of amyloid induced neurotoxicity

Amyloids are highly organized fibril aggregates arise from inappropriately folded form of the protein or polypeptide precursors under both physiological as well as simulated ambience. Amyloid synthesis is a multistep process that involves formation of several metastable intermediates. Among various...

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Detalles Bibliográficos
Autores principales: Kazmi, Shadab, Mujeeb, Anzar Abdul, Owais, Mohammad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251898/
https://www.ncbi.nlm.nih.gov/pubmed/30470780
http://dx.doi.org/10.1038/s41598-018-35645-4