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Cell Cycle Heterogeneity Can Generate Robust Cell Type Proportioning

Cell-cell heterogeneity can facilitate lineage choice during embryonic development because it primes cells to respond to differentiation cues. However, remarkably little is known about the origin of heterogeneity or whether intrinsic and extrinsic variation can be controlled to generate reproducible...

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Detalles Bibliográficos
Autores principales: Gruenheit, Nicole, Parkinson, Katie, Brimson, Christopher A., Kuwana, Satoshi, Johnson, Edward J., Nagayama, Koki, Llewellyn, Jack, Salvidge, William M., Stewart, Balint, Keller, Thomas, van Zon, Wouter, Cotter, Simon L., Thompson, Christopher R.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251973/
https://www.ncbi.nlm.nih.gov/pubmed/30473004
http://dx.doi.org/10.1016/j.devcel.2018.09.023