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Cell Cycle Heterogeneity Can Generate Robust Cell Type Proportioning
Cell-cell heterogeneity can facilitate lineage choice during embryonic development because it primes cells to respond to differentiation cues. However, remarkably little is known about the origin of heterogeneity or whether intrinsic and extrinsic variation can be controlled to generate reproducible...
Autores principales: | Gruenheit, Nicole, Parkinson, Katie, Brimson, Christopher A., Kuwana, Satoshi, Johnson, Edward J., Nagayama, Koki, Llewellyn, Jack, Salvidge, William M., Stewart, Balint, Keller, Thomas, van Zon, Wouter, Cotter, Simon L., Thompson, Christopher R.L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251973/ https://www.ncbi.nlm.nih.gov/pubmed/30473004 http://dx.doi.org/10.1016/j.devcel.2018.09.023 |
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