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Oxidative Stress in Cells with Extra Centrosomes Drives Non-Cell-Autonomous Invasion

Centrosomal abnormalities, in particular centrosome amplification, are recurrent features of human tumors. Enforced centrosome amplification in vivo plays a role in tumor initiation and progression. However, centrosome amplification occurs only in a subset of cancer cells, and thus, partly due to th...

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Detalles Bibliográficos
Autores principales: Arnandis, Teresa, Monteiro, Pedro, Adams, Sophie D., Bridgeman, Victoria Louise, Rajeeve, Vinothini, Gadaleta, Emanuela, Marzec, Jacek, Chelala, Claude, Malanchi, Ilaria, Cutillas, Pedro R., Godinho, Susana A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6251975/
https://www.ncbi.nlm.nih.gov/pubmed/30458137
http://dx.doi.org/10.1016/j.devcel.2018.10.026