A systematic review of the validity of patient derived xenograft (PDX) models: the implications for translational research and personalised medicine

Patient-derived xenograft (PDX) models are increasingly being used in oncology drug development because they offer greater predictive value than traditional cell line models. Using novel tools to critique model validity and reliability we performed a systematic review to identify all original public...

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Detalles Bibliográficos
Autores principales: Collins, Anne T., Lang, Shona H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2018
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252062/
https://www.ncbi.nlm.nih.gov/pubmed/30498642
http://dx.doi.org/10.7717/peerj.5981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252062/
https://www.ncbi.nlm.nih.gov/pubmed/30498642
http://dx.doi.org/10.7717/peerj.5981

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