Mining the cellular inventory of pyridoxal phosphate-dependent enzymes with functionalized cofactor mimics

Pyridoxal phosphate (PLP) is an enzyme cofactor required for the chemical transformation of biological amines in numerous essential cellular processes. PLP-dependent enzymes (PLP-DEs) are ubiquitous and evolutionarily diverse, making their classification based on sequence homology challenging. Here...

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Detalles Bibliográficos
Autores principales: Hoegl, Annabelle, Nodwell, Matthew B., Kirsch, Volker C., Bach, Nina C., Pfanzelt, Martin, Stahl, Matthias, Schneider, Sabine, Sieber, Stephan A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252082/
https://www.ncbi.nlm.nih.gov/pubmed/30297752
http://dx.doi.org/10.1038/s41557-018-0144-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252082/
https://www.ncbi.nlm.nih.gov/pubmed/30297752
http://dx.doi.org/10.1038/s41557-018-0144-2

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