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Association of PD-1 and PD-L1 Genetic Polymorphyisms with Type 1 Diabetes Susceptibility

AIMS: The programmed death- (PD-) 1/PD-1 ligand (PD-L) pathway plays an important role in regulating T cell activation and maintaining peripheral tolerance. Accumulated studies showed that PD-1/PD-L1 pathway was involved in the development of type 1 diabetes (T1DM). Since the genetic background of t...

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Detalles Bibliográficos
Autores principales: Qian, Chenyue, Guo, Heming, Chen, Xiaohong, Shi, Aiming, Li, Sicheng, Wang, Xin, Pan, Jie, Fang, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252202/
https://www.ncbi.nlm.nih.gov/pubmed/30534571
http://dx.doi.org/10.1155/2018/1614683