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Opening the Blood-Brain Barrier and Improving the Efficacy of Temozolomide Treatments of Glioblastoma Using Pulsed, Focused Ultrasound with a Microbubble Contrast Agent

OBJECTIVE: To explore the effects of pulsed, focused, and microbubble contrast agent-enhanced ultrasonography (mCEUS) on blood-brain barrier (BBB) permeability and the efficacy temozolomide for glioblastoma. METHODS: Wistar rats (n = 30) were divided into three groups (n = 10 per group) to determine...

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Detalles Bibliográficos
Autores principales: Dong, Qian, He, Lin, Chen, Linbo, Deng, Qiongzhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252217/
https://www.ncbi.nlm.nih.gov/pubmed/30534564
http://dx.doi.org/10.1155/2018/6501508