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Ameliorating effects of bortezomib, a proteasome inhibitor, on development of dextran sulfate sodium-induced murine colitis

We examined the effect of bortezomib, a proteasome inhibitor, on the development of dextran sulfate sodium (DSS)-induced colitis in mice. DSS-colitis was induced by the administration of 3% DSS in water in C57BL/6J mice. Bortezomib was intraperitoneally administered daily for 9 days from the start o...

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Detalles Bibliográficos
Autores principales: Sakai, Shigeki, Nishida, Atsushi, Ohno, Masashi, Inatomi, Osamu, Bamba, Shigeki, Sugimoto, Mitsushige, Kawahara, Masahiro, Andoh, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252295/
https://www.ncbi.nlm.nih.gov/pubmed/30487672
http://dx.doi.org/10.3164/jcbn.18-42