Antitumor Activity of Auger Electron Emitter (111)In Delivered by Modular Nanotransporter for Treatment of Bladder Cancer With EGFR Overexpression

Gamma-ray emitting (111)In, which is extensively used for imaging, is also a source of short-range Auger electrons (AE). While exhibiting negligible effect outside cells, these AE become highly toxic near DNA within the cell nucleus. Therefore, these radionuclides can be used as a therapeutic antica...

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Detalles Bibliográficos
Autores principales: Rosenkranz, Andrey A., Slastnikova, Tatiana A., Karmakova, Tatiana A., Vorontsova, Maria S., Morozova, Natalia B., Petriev, Vasiliy M., Abrosimov, Alexey S., Khramtsov, Yuri V., Lupanova, Tatiana N., Ulasov, Alexey V., Yakubovskaya, Raisa I., Georgiev, Georgii P., Sobolev, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252321/
https://www.ncbi.nlm.nih.gov/pubmed/30510514
http://dx.doi.org/10.3389/fphar.2018.01331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252321/
https://www.ncbi.nlm.nih.gov/pubmed/30510514
http://dx.doi.org/10.3389/fphar.2018.01331

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