Population Pharmacokinetic/Pharmacodynamic Model-Guided Dosing Optimization of a Novel Sedative HR7056 in Chinese Healthy Subjects

HR7056 is a new benzodiazepine, showing more faster acting onset and recovery than currently available short-acting sedatives. To avoid inadequate anesthesia and predict return of cognition, allowing for immediate neurological evaluation, HR7056 pharmacokinetics and pharmacodynamics were characteriz...

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Detalles Bibliográficos
Autores principales: Zhou, Ying, Hu, Pei, Huang, Yuguang, Sang, Nuoer, Song, Kaicheng, Wang, Hongyun, Wen, Jinhua, Jiang, Ji, Chen, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252322/
https://www.ncbi.nlm.nih.gov/pubmed/30510509
http://dx.doi.org/10.3389/fphar.2018.01316

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252322/
https://www.ncbi.nlm.nih.gov/pubmed/30510509
http://dx.doi.org/10.3389/fphar.2018.01316

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