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PPIs Are Not Responsible for Elevating Cardiovascular Risk in Patients on Clopidogrel—A Systematic Review and Meta-Analysis

Background: Clopidogrel and proton pump inhibitors (PPIs) are metabolized by cytochrome P450 enzymes. Contradictory results have been reported on possible complications of simultaneous PPI and clopidogrel use. Our aim was to investigate the clinical relevance of this debate with a systematic review...

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Detalles Bibliográficos
Autores principales: Demcsák, Alexandra, Lantos, Tamás, Bálint, Emese Réka, Hartmann, Petra, Vincze, Áron, Bajor, Judit, Czopf, László, Alizadeh, Hussain, Gyöngyi, Zoltán, Márta, Katalin, Mikó, Alexandra, Szakács, Zsolt, Pécsi, Dániel, Hegyi, Péter, Szabó, Imre László
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252380/
https://www.ncbi.nlm.nih.gov/pubmed/30510515
http://dx.doi.org/10.3389/fphys.2018.01550