1951. Nephrotoxicity Associated With Imipenem/Cilastatin/Relebactam (IMI/REL) vs. Imipenem/Cilastatin Plus Colistin (IMI+CST) in Patients With Imipenem-Nonsusceptible (NS) Bacterial Infections

BACKGROUND: Nephrotoxicity is a common complication of CST-based therapy, limiting its use to treat carbapenem-resistant bacterial infections. REL is a novel β-lactamase inhibitor that restores imipenem activity against many imipenem-NS strains of Gram-negative pathogens. IMI/REL was shown to be as...

Descripción completa

Detalles Bibliográficos
Autores principales: Brown, Michelle, Motsch, Johann, Kaye, Keith, File, Thomas, Boucher, Helen W, Vendetti, Neika, Aggrey, Angela, Joeng, Hee-Koung, Tipping, Robert, Du, Jiejun, Depestel, Daryl D, Butterton, Joan, Kartsonis, Nicholas A, Paschke, Amanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252440/
http://dx.doi.org/10.1093/ofid/ofy210.1607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252440/
http://dx.doi.org/10.1093/ofid/ofy210.1607

Ejemplares similares