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2247. Antiretrovirals Perturb Cholesterol Biosynthesis in PBMCs of HIV-Infected Individuals

BACKGROUND: Although antiretroviral therapy (ART) has resulted in a marked decrease in AIDS-related morbidity and mortality, the therapeutic benefit is often limited by side effects such as metabolic derangement, lipodystrophy, hyperlipidemia and cardiovascular diseases. The underlying mechanisms of...

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Detalles Bibliográficos
Autores principales: Sopeyin, Anuoluwapo, Li, Min, Paintsil, Elijah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252475/
http://dx.doi.org/10.1093/ofid/ofy210.1900