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1390. Pharmacokinetic-Pharmacodynamic (PK-PD) Target Attainment Analyses to Support Rezafungin (RZF) Dose Selection in Treatment of Candida

BACKGROUND: RZF is a novel antifungal of the echinocandin class with distinctive pharmacokinetics that support weekly dosing intervals. RZF is being developed for the treatment of candidemia and invasive candidiasis (IC) and the prevention of invasive fungal infections. A previously developed popula...

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Detalles Bibliográficos
Autores principales: Lakota, Elizabeth A, Ganesan, Harish, Flanagan, Shawn, Ong, Voon, Sandison, Taylor, Bhavnani, Sujata M, Rubino, Christopher M, Ambrose, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252571/
http://dx.doi.org/10.1093/ofid/ofy210.1221