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1381. Impact of Total Body Weight on Efficacy of Ceftriaxone in Obese Patients

BACKGROUND: Ceftriaxone (CRO), while highly protein bound, retains a small volume of distribution. Obese patients have larger volumes of distributions and higher clearance than nonobese patients. The effect of these differences on the pharmacokinetics and efficacy of CRO remain unclear. METHODS: Thi...

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Detalles Bibliográficos
Autores principales: Wagner, Jamie L, Loper, J Taylor, Morrison, Austin R, Stover, Kayla R, Barber, Katie E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252697/
http://dx.doi.org/10.1093/ofid/ofy210.1212