1396. Predictions of Isavuconazonium Sulfate Dosage in Patients Aged 6 Months: <18 Years by Physiologically Based Pharmacokinetic Modeling

BACKGROUND: Best practice to establish dosage regimens for “first-in-pediatric” clinical trials requires knowledge of efficacious and safe exposures in adults. METHODS: Pediatric equivalent doses were predicted for patients aged 6 months and <18 years using physiologically based pharmacokinetic (...

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Detalles Bibliográficos
Autores principales: Desai, Amit, Kovanda, Laura, Lademacher, Christopher, Hope, William, Neely, Michael, Bonate, Peter, Edginton, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252833/
http://dx.doi.org/10.1093/ofid/ofy210.1227

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252833/
http://dx.doi.org/10.1093/ofid/ofy210.1227

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