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1643. Pharmacodynamics (PD) of Daptomycin (DAP) in Combination Therapy for Enterococcal Bloodstream Infection (BSI)

BACKGROUND: DAP is frequently employed in combination with a second antibiotic for enterococcal BSI. We previously observed that a free drug area under the curve to MIC ratio (fAUC/MIC) >27.43 was predictive of survival when DAP was administered as monotherapy. The extent to which combination the...

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Detalles Bibliográficos
Autores principales: Avery, Lindsay, Kuti, Joseph L, Weisser, Maja, Egli, Adrian, Rybak, Michael J, Zasowski, Evan J, Arias, Cesar, Contreras, German, Chong, Pearlie, Aitken, Samuel L, DiPippo, Adam J, Wang, Jann-Tay, Britt, Nicholas S, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252841/
http://dx.doi.org/10.1093/ofid/ofy209.113