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1954. A Randomized Study to Evaluate the Shedding and Immunogenicity of H1N1 Strains in Trivalent and Quadrivalent Formulations of FluMist in Children 24 to <48 Months of Age

BACKGROUND: The quadrivalent live attenuated influenza vaccine (LAIV4) showed reduced effectiveness for the A/H1N1 component of the vaccine in 2013–2014 and 2015–2016. To address this, new assays were used to identify H1N1 LAIV strains with improved replicative fitness and immunogenicity. In this st...

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Detalles Bibliográficos
Autores principales: Mallory, Raburn, Nyborg, Andrew C, Kalyani, Rubana, Tsai, Lan-Feng, Block, Stan L, Dubovsky, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252885/
http://dx.doi.org/10.1093/ofid/ofy210.1610