1397. Comparative Efficacy of Human-Simulated Epithelial Lining Fluid (ELF) Exposures of Tedizolid (TZD) Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Neutropenic (I−) vs. Immunocompetent (I+) Murine Models of Pneumonia

BACKGROUND: TZD is an oxazolidinone with potent in vitro activity against Gram-positive pathogens, including MRSA. Limited data currently exist on the efficacy of TZD in the presence of neutropenia. Herein, we investigate the comparative efficacy of human-simulated ELF exposures of TZD against MRSA...

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Detalles Bibliográficos
Autores principales: Kidd, James M, Abdelraouf, Kamilia, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252954/
http://dx.doi.org/10.1093/ofid/ofy210.1228

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252954/
http://dx.doi.org/10.1093/ofid/ofy210.1228

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