Cargando…

1397. Comparative Efficacy of Human-Simulated Epithelial Lining Fluid (ELF) Exposures of Tedizolid (TZD) Against Methicillin-resistant Staphylococcus Aureus (MRSA) in Neutropenic (I−) vs. Immunocompetent (I+) Murine Models of Pneumonia

BACKGROUND: TZD is an oxazolidinone with potent in vitro activity against Gram-positive pathogens, including MRSA. Limited data currently exist on the efficacy of TZD in the presence of neutropenia. Herein, we investigate the comparative efficacy of human-simulated ELF exposures of TZD against MRSA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kidd, James M, Abdelraouf, Kamilia, Nicolau, David P
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252954/ http://dx.doi.org/10.1093/ofid/ofy210.1228

Ejemplares similares

675. Efficacy of Human-Simulated Bronchopulmonary Exposures of Cefepime and Zidebactam (WCK 5222) Against Multidrug-Resistant (MDR) Pseudomonas aeruginosa (PSA) in a Neutropenic Murine Pneumonia Model
por: Kidd, James M, et al.
Publicado: (2019)

1368. Assessment of the In Vivo Efficacy of Human-Simulated Epithelial Lining Fluid (ELF) Exposure of Meropenem/Nacubactam (MEM/NAC) Combination Against β-Lactamase-Producing Enterobacteriaceae in Neutropenic Lung Infection Model
por: Asempa, Tomefa E, et al.
Publicado: (2018)

In vivo efficacy of WCK 6777 (ertapenem/zidebactam) against carbapenemase-producing Klebsiella pneumoniae in the neutropenic murine pneumonia model
por: Gethers, Matthew, et al.
Publicado: (2022)

471. Safety and Efficacy of Oral and/or Intravenous Tedizolid Phosphate (TZD) in Adolescents with Acute Bacterial Skin and Skin Structure Tissue Infections (ABSSSI)
por: Bradley, John S, et al.
Publicado: (2019)

Assessment of the In Vivo Efficacy of Plazomicin (PLZ) Alone or in Combination with Meropenem (MEM) or Tigecycline (TGC) against Enterobacteriaceae (EB) Isolates Exhibiting Various Resistance Mechanisms in an Immunocompetent (I+) Murine Septicemia Model
por: Abdelraouf, Kamilia, et al.
Publicado: (2017)

1405. Efficacy of the Human-Simulated Regimen (HSR) of Cefepime (FEP)/VNRX-5133 Combination Against Serine β-Lactamase-Producing Gram-negative Bacteria in the Neutropenic Murine Thigh Infection Model
por: Abdelraouf, Kamilia, et al.
Publicado: (2018)

1245. In Vivo Efficacy of WCK 4282 (High Dose Cefepime [FEP]-Tazobactam [TZB]) Against β-Lactamase-Producing (BLP) Gram-Negative Bacteria in a Neutropenic Murine Pneumonia Model
por: Lasko, Maxwell J, et al.
Publicado: (2020)

712. Identification of a Novel Tedizolid Resistance Mutation in rpoB of Methicillin-Resistant Staphylococcus aureus
por: Werth, Brian, et al.
Publicado: (2018)

Divergent Synthesis of Novel Cylindrocyclophanes that Inhibit Methicillin‐Resistant Staphylococcus aureus (MRSA)
por: Freudenreich, Julien J., et al.
Publicado: (2020)

1336. Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) Against Carbapenems-Resistant Acinetobacter baumannii (CR-ACBN) in the Neutropenic Murine Thigh Infection Model
por: Abuhussain, Safa Almarzoky, et al.
Publicado: (2018)

1244. Assessment of the In Vivo Activity of Human-Simulated Exposure of WCK 4282 (High Dose Cefepime [FEP]-Tazobactam [TZB]) against Enterobacterales (EB) and Pseudomonas aeruginosa (PA) in the Neutropenic Murine Thigh Infection Model
por: Gill, Christian M, et al.
Publicado: (2020)

Daptomycin susceptibility of methicillin resistant Staphylococcus aureus (MRSA)
por: Kaur, Rajneet, et al.
Publicado: (2012)

682. In Vivo Pharmacodynamics of VNRX-7145 in the Neutropenic Murine Thigh Infection Model When Administered in Combination with Humanized Exposures of Twice Daily Ceftibuten (CTB) Against Serine β-Lactamase-Producing Enterobacteriaceae (SBL-EB)
por: Avery, Lindsay M, et al.
Publicado: (2019)

Detection of inducible clindamycin resistance (MLSB(i)) among methicillin-resistant Staphylococcus aureus (MRSA) from Libya
por: Ahmed, Mohamed O., et al.
Publicado: (2010)

Methicillin-Resistant Staphylococcus aureus (MRSA) in Artisanal Cheeses in México
por: Adame-Gómez, Roberto, et al.
Publicado: (2018)

2841. A Phase 3, Randomized, Double-Blind Study Comparing Tedizolid Phosphate (TZD) and Linezolid (LZD) for Treatment of Ventilated Gram-Positive (G+) Nosocomial Pneumonia
por: Wunderink, Richard G, et al.
Publicado: (2019)

Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model
por: Fischer, Evelin, et al.
Publicado: (2017)

Impact of target site distribution for Type I restriction enzymes on the evolution of methicillin-resistant Staphylococcus aureus (MRSA) populations
por: Roberts, Gareth A., et al.
Publicado: (2013)

Methicillin-Resistant Staphylococcus aureus (MRSA) Is Increasing in Norway: A Time Series Analysis of Reported MRSA and Methicillin-Sensitive S. aureus Cases, 1997–2010
por: Moxnes, John F., et al.
Publicado: (2013)

In vitro transfer of methicillin resistance determinants mecA from methicillin resistant Staphylococcus aureus (MRSA) to methicillin susceptible Staphylococcus aureus (MSSA)
por: Bitrus, Asinamai Athliamai, et al.
Publicado: (2017)

1553. Human-Simulated Pharmacokinetic Profiles of Cefiderocol and Meropenem Are Conserved in Murine Models of Thigh Infection With or Without Iron Overload
por: Kidd, James M, et al.
Publicado: (2019)

1544. Efficacy of Human-Simulated Cefiderocol Exposure Against Gram-Negative Bacteria in an Iron-Overloaded Murine Thigh Infection Model
por: Kidd, James M, et al.
Publicado: (2019)

Dalbavancin reduces biofilms of methicillin-resistant Staphylococcus aureus (MRSA) and methicillin-resistant Staphylococcus epidermidis (MRSE)
por: Knafl, D., et al.
Publicado: (2016)

Antibacterial potential of Malaysian ethnomedicinal plants against methicillin-susceptible Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA)
por: Yi Xin, Low, et al.
Publicado: (2021)

Hospital-associated methicillin-resistant Staphylococcus aureus (HA-MRSA) in Italy
por: Campanile, Floriana, et al.
Publicado: (2009)

Methicillin-resistant staphylococcus aureus (MRSA) carriage in a dermatology unit
por: Pacheco, Renata L., et al.
Publicado: (2011)

Misidentification of methicillin-resistant Staphylococcus aureus (MRSA) in hospitals in Tripoli, Libya
por: Ahmed, Mohamed O., et al.
Publicado: (2010)

Methicillin resistant Staphylococcus aureus (MRSA) in India: Prevalence & susceptibility pattern
por: Joshi, Sangeeta, et al.
Publicado: (2013)

Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in retail food in Singapore
por: Aung, Kyaw Thu, et al.
Publicado: (2017)

New combination approaches to combat methicillin-resistant Staphylococcus aureus (MRSA)
por: Sharaf, Mohamed H., et al.
Publicado: (2021)

Drivers of methicillin-resistant Staphylococcus aureus (MRSA) lineage replacement in China
por: Chen, Hongbin, et al.
Publicado: (2021)

The antibacterial mechanism of oridonin against methicillin-resistant Staphylococcus aureus (MRSA)
por: Yuan, Zhongwei, et al.
Publicado: (2019)

In vitro susceptibility of methicillin-resistant Staphylococcus aureus isolates from skin and soft tissue infections to vancomycin, daptomycin, linezolid and tedizolid
por: Vanegas Múnera, Johanna Marcela, et al.
Publicado: (2017)

Lower Methicillin-Resistant Staphylococcus aureus (MRSA) Acquisition and Nosocomial Cultures While on Anti-MRSA Antibiotics?
por: Jones, Makoto, et al.
Publicado: (2015)

A Rare Case of Acute Cholecystitis Caused by Methicillin-Resistant Staphylococcus aureus (MRSA) in an Immunocompetent Person in the Absence of Bacteremia or Pre-Existing Conditions
por: Choudhury, Ajanta, et al.
Publicado: (2023)

Community-associated Methicillin-resistant Staphylococcus aureus pericarditis in an immunocompetent patient
por: Jevtic, Dorde, et al.
Publicado: (2022)

Mortality after infection with methicillin-resistant Staphylococcus aureus (MRSA) diagnosed in the community
por: Delaney, JA 'Chris', et al.
Publicado: (2008)

Telavancin for the treatment of nosocomial pneumonia caused by methicillin-resistant Staphylococcus aureus (MRSA)
por: Hooper, Candace Y, et al.
Publicado: (2012)

Synergism between Medihoney and Rifampicin against Methicillin-Resistant Staphylococcus aureus (MRSA)
por: Müller, Patrick, et al.
Publicado: (2013)

Analysis of Virulence Genes Among Methicillin Resistant Staphylococcus aureus (MRSA) Strains
por: Hoseini Alfatemi, Seyedeh Mahsan, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_mjbbp0aqhnm79bbbh2arih8ig7