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1644. A Potent Broadly Neutralizing Antibody Isolated From Human Memory B-cells Binding to Conserved Site IV on the RSV F Protein

BACKGROUND: Respiratory syncytial virus (RSV) infection is a major public health burden for infants and the elderly worldwide. Currently, there are no approved vaccines and only one moderately effective marketed antibody (Synagis®) for the prevention of RSV infection in high-risk infants. Sampling t...

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Detalles Bibliográficos
Autores principales: Vora, Kalpit, Chen, Zhifeng, Su, Hua-Poo, Tang, Aimin, Cox, Kara, Callahan, Cheryl, Zhang, Lan, Patel, Sangita, Nahas, Debbie, Citron, Mike, Cejas, Pedro, Swoyer, Ryan, Luo, Bin, Eddins, Michael, Reid, John, Fridman, Arthur, Galli, Jennifer, Cosmi, Scott, Dhanasekeran, Govindarajan, Wen, Zhiyun, He, Xi, Wang, Dai, Heidecker, Gwen, Flynn, Jessica, Cook, James, Soisson, Stephen, Casimiro, Danilo, Bett, Andrew, Blair, Wade, Distefano, Daniel, Haines, Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6252969/
http://dx.doi.org/10.1093/ofid/ofy209.114