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1400. Mass Balance, Metabolism, and Excretion of [(14)C]-Plazomicin in Healthy Human Subjects

BACKGROUND: Plazomicin is a next-generation aminoglycoside (AG) with a structure that protects it from common AG resistance mechanisms in Enterobacteriaceae, and with in vitro activity against extended spectrum β-lactamase-producing and carbapenem-resistant Enterobacteriaceae. The purpose of this st...

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Detalles Bibliográficos
Autores principales: Choi, Taylor, Seroogy, Julie D, Sanghvi, Mitesh, Dhuria, Shyeilla V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253090/
http://dx.doi.org/10.1093/ofid/ofy210.1231