Cargando…
1400. Mass Balance, Metabolism, and Excretion of [(14)C]-Plazomicin in Healthy Human Subjects
BACKGROUND: Plazomicin is a next-generation aminoglycoside (AG) with a structure that protects it from common AG resistance mechanisms in Enterobacteriaceae, and with in vitro activity against extended spectrum β-lactamase-producing and carbapenem-resistant Enterobacteriaceae. The purpose of this st...
Autores principales: | Choi, Taylor, Seroogy, Julie D, Sanghvi, Mitesh, Dhuria, Shyeilla V |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253090/ http://dx.doi.org/10.1093/ofid/ofy210.1231 |
Ejemplares similares
-
A Phase 1 Study To Assess the Pharmacokinetics of Intravenous Plazomicin in Adult Subjects with Varying Degrees of Renal Function
por: Komirenko, Allison S., et al.
Publicado: (2018) -
1286. Pharmacokinetics, Excretion, and Mass Balance of [(14)C]-Rezafungin Following Intravenous (IV) Administration in Healthy Adults
por: Ong, Voon, et al.
Publicado: (2020) -
Metabolism, Excretion, and Mass Balance of [(14)C]-Rezafungin in Animals and Humans
por: Ong, Voon, et al.
Publicado: (2022) -
1227. Plazomicin Susceptibility Testing using ETEST(®) MIC for Enterobacterales
por: Ying, Yun, et al.
Publicado: (2020) -
Population Pharmacokinetic Analyses for Plazomicin Using Pooled Data from Phase 1, 2, and 3 Clinical Studies
por: Trang, Michael, et al.
Publicado: (2019)