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1337. SYN-004 (Ribaxamase) Protects the Gut Microbiome of Patients Treated With Ceftriaxone From Disruption and Reduces the Emergence of Antimicrobial Resistance

BACKGROUND: When β-lactam antibiotics are administered intravenously, a significant portion of each dose can be excreted through the bile into the intestine. This excess antibiotic disrupts the balance of the gut microbiome making the recipient more susceptible to certain infections and can lead to...

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Detalles Bibliográficos
Autores principales: Kokai-Kun, John, Le, Charles, Trout, Kenneth, Cope, Julia, Sliman, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253211/
http://dx.doi.org/10.1093/ofid/ofy210.1169