1343. Prophylactic Dosing of Baloxavir Acid Eliminates Mortality in Mice Lethal Influenza A Virus Infection Model

BACKGROUND: Baloxavir acid (BXA), an active form of orally available prodrug baloxavir marboxil (BXM, formerly S-033188), is a novel small molecule inhibitor of cap-dependent endonuclease (CEN) of influenza A and B virus, and was recently launched for the treatment of acute and uncomplicated influen...

Descripción completa

Detalles Bibliográficos
Autores principales: Shano, Shinya, Fukao, Keita, Noshi, Takeshi, Sato, Kenji, Sakuramoto, Masashi, Baba, Kaoru, Shishido, Takao, Naito, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253271/
http://dx.doi.org/10.1093/ofid/ofy210.1174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253271/
http://dx.doi.org/10.1093/ofid/ofy210.1174

Ejemplares similares