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382. Virulence in Candida glabrata Is Not Attenuated by FKS Mutations but Associated With the Frequency of Cells With Distinct Morphology

BACKGROUND: Echinocandins are the first-line treatment for C. glabrata; however, echinocandin resistance is increasingly reported. Acquired FKS-mediated echinocandin resistance has been associated with the upregulation of chitin synthesis and attenuated fitness and virulence in C. albicans; however,...

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Detalles Bibliográficos
Autores principales: Hu, Chenlin, Fong, Gary, Beyda, Nicholas D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253357/
http://dx.doi.org/10.1093/ofid/ofy210.393