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382. Virulence in Candida glabrata Is Not Attenuated by FKS Mutations but Associated With the Frequency of Cells With Distinct Morphology
BACKGROUND: Echinocandins are the first-line treatment for C. glabrata; however, echinocandin resistance is increasingly reported. Acquired FKS-mediated echinocandin resistance has been associated with the upregulation of chitin synthesis and attenuated fitness and virulence in C. albicans; however,...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253357/ http://dx.doi.org/10.1093/ofid/ofy210.393 |