1408. Population Pharmacokinetic (PK) Model to Describe Epithelial Lining Fluid (ELF) Penetration of ASN-1 and ASN-2 after ASN100 Administration to Healthy Subjects

BACKGROUND: ASN100 is a combination of two co-administered fully human monoclonal antibodies (mAbs), ASN-1 and ASN-2, that together neutralize the six cytotoxins critical to S. aureus pneumonia pathogenesis. ASN100 is in development for prevention of S. aureus pneumonia in mechanically ventilated pa...

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Detalles Bibliográficos
Autores principales: Van Wart, Scott A, Stevens, Christopher, Magyarics, Zoltan, Luperchio, Steven A, Rubino, Christopher M, Ambrose, Paul G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253428/
http://dx.doi.org/10.1093/ofid/ofy210.1239

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253428/
http://dx.doi.org/10.1093/ofid/ofy210.1239

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