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1415. Implementation and Validation of a Vancomycin AUC/MIC Calculator and Dosing Protocol at a Large Community Hospital

BACKGROUND: Current IDSA guidelines recommend targeting a vancomycin trough between 15 and 20 mg/L to achieve an AUC/MIC ≥ 400; however, recent literature shows increased rates of nephrotoxicity within this range and the target AUC/MIC ratio may be achieved with lower troughs. We sought to determine...

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Detalles Bibliográficos
Autores principales: Seddon, Megan, Scorgie, Kevin, Kutner, Sara, McMahon, Andre, Kisgen, Jamie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253667/
http://dx.doi.org/10.1093/ofid/ofy210.1246