Cargando…
787. The Addition of Avibactam Augments the Activity of Piperacillin Against Mycobacterium abscessus in vitro, and Is Effective in Treating M. abscessus Infection in a Galleria mellonella in vivo Model
BACKGROUND: Mycobacterium abscessus is an emerging multi-drug-resistant pathogen, harboring the β-lactamse Bla(MAB). Avibactam is a non-β-lactam, β-lactamase inhibitor shown to inhibit Bla(MAB) and improve the efficacy of ampicillin for M. abscessus infections in in vitro and in vivo models. Whether...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2018
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253713/ http://dx.doi.org/10.1093/ofid/ofy210.794 |