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1984. Ceftriaxone-Sulbactam-EDTA vs. Meropenem: Analysis of Failed Patients With Assessment of MIC Increases and Changes in Genotypic Profile in PLEA (a Phase 3, Randomized, Double-Blind Clinical Trial in Adults With Complicated Urinary Tract Infections or Acute Pyelonephritis)

BACKGROUND: Ceftriaxone–sulbactam–EDTA (CSE) is a novel combination being developed to treat serious infections caused by Gram-negative bacteria. In vitro molecular biology studies have shown that the addition of EDTA in the combination helps to prevent horizontal gene transfer during conjugation by...

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Detalles Bibliográficos
Autores principales: Mir, Mohd Amin, Chaudhary, Saransh, Chaudhary, Manu, Pyasi, Anurag, Patil, N S, Girotra, Ruchi, Narang, Salil, Fatima, Nazish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253802/
http://dx.doi.org/10.1093/ofid/ofy210.1640