Screening of Agelasine D and Analogs for Inhibitory Activity against Pathogenic Protozoa; Identification of Hits for Visceral Leishmaniasis and Chagas Disease

There is an urgent need for novel and improved drugs against several tropical diseases caused by protozoa. The marine sponge (Agelas sp.) metabolite agelasine D, as well as other agelasine analogs and related structures were screened for inhibitory activity against Plasmodium falciparum, Leishmania...

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Detalles Bibliográficos
Autores principales: Vik, Anders, Proszenyák, Ágnes, Vermeersch, Marieke, Cos, Paul, Maes, Louis, Gundersen, Lise-Lotte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253839/
https://www.ncbi.nlm.nih.gov/pubmed/19136916
http://dx.doi.org/10.3390/molecules14010279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253839/
https://www.ncbi.nlm.nih.gov/pubmed/19136916
http://dx.doi.org/10.3390/molecules14010279

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