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Screening of Agelasine D and Analogs for Inhibitory Activity against Pathogenic Protozoa; Identification of Hits for Visceral Leishmaniasis and Chagas Disease
There is an urgent need for novel and improved drugs against several tropical diseases caused by protozoa. The marine sponge (Agelas sp.) metabolite agelasine D, as well as other agelasine analogs and related structures were screened for inhibitory activity against Plasmodium falciparum, Leishmania...
Autores principales: | Vik, Anders, Proszenyák, Ágnes, Vermeersch, Marieke, Cos, Paul, Maes, Louis, Gundersen, Lise-Lotte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Molecular Diversity Preservation International
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253839/ https://www.ncbi.nlm.nih.gov/pubmed/19136916 http://dx.doi.org/10.3390/molecules14010279 |
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