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The Inhibitory Action of Kohamaic Acid A Derivatives on Mammalian DNA Polymerase β

We previously isolated a novel natural product, designated kohamaic acid A (KA-A, compound 1), as an inhibitor of the first cleavage of fertilized sea urchin eggs, and found that this compound could selectively inhibit the activities of mammalian DNA polymerases (pols). In this paper, we investigate...

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Detalles Bibliográficos
Autores principales: Mizushina, Yoshiyuki, Manita, Daisuke, Takeuchi, Toshifumi, Sugawara, Fumio, Kumamoto-Yonezawa, Yuko, Matsui, Yuki, Takemura, Masaharu, Sasaki, Mitsuru, Yoshida, Hiromi, Takikawa, Hirosato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253949/
https://www.ncbi.nlm.nih.gov/pubmed/19127241
http://dx.doi.org/10.3390/molecules14010102