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712. Identification of a Novel Tedizolid Resistance Mutation in rpoB of Methicillin-Resistant Staphylococcus aureus

BACKGROUND: Tedizolid (TDZ) is an oxazolidinone antimicrobial with broad-spectrum activity against Gram-positive bacteria including methicillin-resistant S. aureus (MRSA). Resistance to TDZ is uncommon but mutations in the 23S rRNA target as well as in the transferable rRNA methyltransferase gene cf...

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Detalles Bibliográficos
Autores principales: Werth, Brian, Penewit, Kelsi, Salipante, Stephen, Shen, Tianwei, Xu, Libin, Nath, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253963/
http://dx.doi.org/10.1093/ofid/ofy210.719