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636. The Hepcidin-25 and Iron Kinetics During the Acute Phase of Systemic Infection

BACKGROUND: Hepcidin-25, a central regulator of iron metabolism, can decrease serum iron levels by inhibiting the iron transporter ferroportin. Production of hepcidin-25 in hepatocytes is tightly regulated by various stimulations and is promoted by inflammation via the IL-6 pathway. The role of hepc...

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Detalles Bibliográficos
Autores principales: Moro, Hiroshi, Bamba, Yuuki, Nagano, Kei, Koizumi, Takeshi, Aoki, Nobumasa, Ohshima, Yasuyoshi, Watanabe, Satoshi, Koya, Toshiyuki, Takada, Toshinori, Kikuchi, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6253969/
http://dx.doi.org/10.1093/ofid/ofy210.643