Synthesis of 1α,25-Dihydroxyvitamin D Analogues Featuring a S(2)-symmetric CD-ring Core

Three analogues of 1α,25-dihydroxyvitamin D(3) (calcitriol), featuring a trans-fused decalin C,D-core with local S(2)-symmetry, and possessing identical side-chain and seco-B,A-ring structures, have been synthesized starting from readily available (4aR,8aS)-octahydronaphthalene-1,5-dione (7). The ve...

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Detalles Bibliográficos
Autores principales: Minne, Garrett, Verlinden, Lieve, Verstuyf, Annemieke, De Clercq, Pierre J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254054/
https://www.ncbi.nlm.nih.gov/pubmed/19255548
http://dx.doi.org/10.3390/molecules14020894

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254054/
https://www.ncbi.nlm.nih.gov/pubmed/19255548
http://dx.doi.org/10.3390/molecules14020894

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