696. Mechanism of Cefiderocol high MIC mutants obtained in non-clinical FoR studies

BACKGROUND: Cefiderocol (S-649266, CFDC) is a novel siderophore cephalosporin with activity against a wide variety of Gram-negative bacteria including carbapenem-resistant strains. We previously reported that CFDC is efficiently transported into Pseudomonas aeruginosa via iron transporter PiuA. In t...

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Detalles Bibliográficos
Autores principales: Ito, Akinobu, Nishikawa, Toru, Ishii, Ryuta, Kuroiwa, Miho, Ishioka, Yoshino, Kurihara, Naoko, Sakikawa, Ikue, Ota, Takeshi, Rokushima, Masatomo, Tsuji, Masakatsu, Sato, Takafumi, Yamano, Yoshinori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254112/
http://dx.doi.org/10.1093/ofid/ofy210.703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254112/
http://dx.doi.org/10.1093/ofid/ofy210.703

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