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QSAR Studies on N-aryl Derivative Activity Towards Alzheimer’s Disease

A Quantitative Structure Activity Relationship (QSAR) study has been an attempted on a series of 88 N-aryl derivatives which display varied inhibitory activity towards both acetylcholinesterase (AChE) and butyrylcholinesterase (BChE), targets in Alzheimer’s drug discovery. QSAR models were derived f...

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Detalles Bibliográficos
Autores principales: Solomon, Kamalakaran Anand, Sundararajan, Srinivasan, Abirami, Veluchamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254147/
https://www.ncbi.nlm.nih.gov/pubmed/19384276
http://dx.doi.org/10.3390/molecules14041448